Amiodarone Drip              
Drip Information     
Dosing Protocol     
 
Dose:  150mg over 10 minutes (15mg/min) bolus, then  
  1mg/min for 6 hours, then 0.5mg/min  
 
In the event of breakthru ventricular fibrillation, the patient   
may be rebolused at 150mg over 10 minutes (15mg/min)  
 
Bolus: Mix 150mg in 100ml of D5W (1.5mg/ml) (may be mixed in a bag)  
Rate: 600ml/hr over 10 minutes  
 
Infusion: Mix 450mg in 250ml of D5W (1.8mg/ml) (MUST be mixed in glass)
Rate: 1mg/min = 33.3ml/hr for 6 hours, then  
  0.5mg/min = 16.7ml/hr   
 
For calculation of other infusion rates  
Amount of amiodarone in Drip: mg  
Volume of infusion bottle: ml  
Concentration of Drip: mg/ml  
Rate of infusion:   mg/min = ml/hr  
 
OR for a given concentration  
Concentration of Drip: mg/ml  
Rate of infusion:   mg/min = ml/hr