Chemotherapy Drugs Reconstitution and Stability Information
Drug	Add listed volume	Final Concentration	Stability at Room Temp	Stability Under Refrigeration	Other Information
Aldesleukin 22 million unit	1.2ml	1.1mg/ml	48 hours	48 hours	1.1mg = 18 million units
Amifostine 500mg	9.7ml	50mg/ml	5 hours	24 hours
Asparaginase 10,000 unis (for IV use)	5ml	2,000 units/ml	8 hours	8 hours
Asparaginase 10,000 unis (for IM use)	2ml	5,000 units/ml	8 hours	8 hours
Bleomycin 15 units (for IM or Subq)	1ml	15 units/ml	14 days	28 days	Mix only in 0.9% NaCl. 1 unit = 1mg
Bleomycin 15 units (for IV)	5ml	3 units/ml	14 days	28 days	Mix only in 0.9% NaCl. 1 unit = 1mg
Bleomycin 30 units (for IM or Subq)	2ml	15 units/ml	14 days	28 days	Mix only in 0.9% NaCl. 1 unit = 1mg
Bleomycin 30 units (for IV)	10ml	3 units/ml	14 days	28 days	Mix only in 0.9% NaCl. 1 unit = 1mg
Busulfan 6mg/ml	---	6mg/ml	8 hours	12 hours
Carboplatin 50mg	5ml	10mg/ml	24 hours	5 days
Carboplatin 150mg	15ml	10mg/ml	24 hours	5 days
Carboplatin 450mg	45ml	10mg/ml	24 hours	5 days
Carmustine 100mg	30ml	3.3mg/ml	8 hours	24 hours	First dilute with 3ml alcohol then 27ml of sterile water. Mix only in 0.9% NaCl.
Cisplatin	---	1mg/ml	24 hours	24 hours
Cladribine 1mg/ml	---	1mg/ml	n/a	14 days	Dilute only in 0.9% NaCl
Cyclophosphamide 100mg	5ml	20mg/ml	24 hours	6 days
Cyclophosphamide 200mg	10ml	20mg/ml	24 hours	6 days
Cyclophosphamide 500mg	25ml	20mg/ml	24 hours	6 days
Cyclophosphamide 1000mg	50ml	20mg/ml	24 hours	6 days
Cyclophosphamide 2000mg	100ml	20mg/ml	24 hours	6 days
Cytarabine 100mg	5ml	20mg/ml	48 hours	n/a
Cytarabine 500mg	10ml	50mg/ml	48 hours	n/a
Cytarabine 1000mg	10ml	100mg/ml	48 hours	n/a
Cytarabine 2000mg	20ml	100mg/ml	48 hours	n/a
Dacarbazine 100mg	9.9ml	10mg/ml	24 hours	96 hours	***Protect from light***
Dacarbazine 200mg	19.7ml	10mg/ml	24 hours	96 hours	***Protect from light***
Dactinomycin 0.5mg	1.1ml	0.5mg/ml	24 hours	24 hours	Don't mix with a diluent w/ a preservative
Daunorubicin 20mg	4ml	5mg/ml	24 hours	48 hours
Dexrazoxane 250mg	25ml	10mg/ml	24 hours	n/a	Do NOT refrigerate
Dexrazoxane 500mg	50ml	10mg/ml	24 hours	n/a	Do NOT refrigerate
Docetaxel 20mg	1.8ml	10mg/ml	8 hours	8 hours	Mix in a glass bottle; stability may be longer (i.e. several weeks; see Trissels)
Docetaxel 80mg	???	10mg/ml	8 hours	8 hours
Doxorubicin liposomal (Doxil) 2mg/ml	---	2mg/ml	n/a	24 hours	Dilute only in D5W **Protect from light**
Doxorubicin 10mg	5ml	2mg/ml	7 days	15 days	***Protect from light***
Doxorubicin 20mg	10ml	2mg/ml	7 days	15 days	***Protect from light***
Doxorubicin 50mg	25ml	2mg/ml	7 days	15 days	***Protect from light***
Doxorubicin 150mg	75ml	2mg/ml	7 days	15 days	***Protect from light***
Doxorubicin 2mg/ml	---	2mg/ml	7 days	15 days	***Protect from light***
Epirubicin 2mg/ml	---	2mg/ml	14 days	14 days
Etoposide 20mg/ml	---	20mg/ml	24 hours	n/a
Etoposide Phosphate 10mg	10ml	10mg/ml	24 hours	7 days
Floxuridine 500mg	5ml	100mg/ml	n/a	14 days
Fludarabine 50mg	2ml	25mg/ml	16 days	16 days
Gemcitabine 200mg	5ml	38mg/ml	24 hours	n/a	Do NOT refrigerate
Gemcitabine 1000mg	25ml	38mg/ml	24 hours	n/a	Do NOT refrigerate
Idarubicin 1mg/ml	---	1mg/ml	72 hours	n/a	***Protect from light***
Ifosfamide 1gm	20ml	50mg/ml	7 days	6 weeks
Ifosfamide 3gm	60ml	50mg/ml	7 days	6 weeks
Interferon alpha 2b 3 million I.U.	1ml	3 million IU/ml	28 days	n/a
Interferon alpha 2b 5 million I.U.	1ml	5 million IU/ml	28 days	n/a
Interferon alpha 2b 10 million I.U.	1ml	10 million IU/ml	28 days	n/a
Interferon alpha 2b 18 million I.U.	1ml	18 million IU/ml	28 days	n/a
Interferon alpha 2b 25 million I.U.	5ml	5 million IU/ml	28 days	n/a
Interferon alpha 2b 50 million I.U.	1ml	50 million IU/ml	28 days	n/a
Irinotecan 20mg/ml	---	20mg/ml	28 days	28 days	***Protect from light***
Leucovorin 100mg	10ml	10mg/ml	n/a	7 days	***Protect from light***
Leucovorin 350mg	34.5ml	10mg/ml	n/a	7 days	***Protect from light***
Leucovorin 350mg/ml	17ml	20mg/ml	n/a	7 days	***Protect from light***
Mechlorethamine 10mg	10ml	1mg/ml	Use Immediately
Melphalan 50mg	10ml	5mg/ml	Use Immediately
Mesna 100mg/ml	---	100mg/ml	24 hours	n/a
Methotrexate 20mg	1ml	20mg/ml	7 days	n/a	***Protect from light***
Methotrexate 1000mg	19.4ml	50mg/ml	7 days	n/a	***Protect from light***
Methotrexate 25mg/ml	---	25mg/ml	7 days	n/a	***Protect from light***
Mitomycin 5mg	10ml	500mcg/ml	7 days	14 days
Mitomycin 20mg	40ml	500mcg/ml	7 days	14 days
Mitomycin 40mg	80ml	500mcg/ml	7 days	14 days
Mitoxantrone 2mg/ml	---	2mg/ml	48 hours	48 hours
Paclitaxel 6mg/ml	---	6mg/ml	48 hours	n/a	Do NOT refrigerate
Pentostatin 10mg	5ml	2mg/ml	48 hours	96 hours	Stability in 0.9% NaCl
Streptozocin 1gm	9.5ml	100mg/ml	48 hours	96 hours
Teniposide 10mg/ml	---	10mg/ml	24 hours	n/a	Do NOT refrigerate
Thiotepa 15mg	1.6ml	15mg/ml	24 hours	48 hours	***Protect from light***
Topotecan 4mg	4ml	1mg/ml	24 hours	n/a
Vinblastine 10mg	10ml	1mg/ml	24 hours	21 days	***Protect from light***
Vincristine 1mg/ml	---	1mg/ml	24 hours	7 days
Vinorelbine 10mg/ml	---	10mg/ml	24 hours	24 hours
*** Stability is that of an IV solution, not that diluted drug in the vial unless otherwise noted